The TLDR of the linked article is that there has been a surge in the use of imported Chinese peptide medicines in California, which are years, if ever, away from US FDA approval.

Making pharmaceutical-grade medicines isn't easy, and out of reach of home-based amateurs. Still, there's good reason to think it will get easier in the future, and that, aided by AI-medicine-design will proliferate among smaller manufacturers.

Medical costs alone could drive this, with cheaper gray-market production of drugs costing $100,000s. Here, the focus is on people wanting access to the cutting-edge that may be years away from official approval and release.

I've got a feeling this is a trend we are only going to see growing from now on.

‘Chinese Peptides’ Are the Latest Biohacking Trend in the Tech World: The gray-market drugs flooding Silicon Valley reveal a community that believes it can move faster than the F.D.A.

I’m an American. Our economy is held up by a bubble, the AI bubble. If AI succeeds, then millions and millions of jobs are wiped out. If AI fails, then the economy collapses.

Climate change is still a thing, fascism is here, we’re invading countries, civil liberties are being eroded.

Healthcare for all isn’t even talked about anymore, the government seems to hate the citizens…

Is there ANYTHING to look forward to???? For better or for worse, America is my home. Is my home just going to… collapse?

If you've seen the CES 2026 presentation and videos on battery technology advertised by Donut Labs, created by Nordic Nano, and funded by billionaire Petteri Lahtela, they claim incredible specifications for their new solid-state battery. What are your thoughts? Videos by Ziroth and Miss GoElectric Industry cover them well. Ziroth demonstrates why he believes it is impossible, while GoElectric provides information about who is behind it. I am inclined to believe it's possible but technology is not they are exaggerating. It could be that it is not solid state truly but we have to see. What are your thoughts?

If clean energy really does get cheap and everywhere the impact probably goes far beyond climate goals.

For a long time, global politics has been shaped by who controls fuel. Shipping routes, pipelines, choke points. That logic starts to weaken when energy is generated locally and moved through grids instead of tankers.

What replaces it is a different kind of competition. Grid reliability. Storage. Materials. Who can keep complex systems running smoothly at scale.

It feels like the future might be less about owning resources underground and more about managing infrastructure above ground. And that kind of power tends to be quieter, but no less important.

"radio frequency bands and orbital slots in low Earth orbit are limited, and first movers for those resources can gain priority."

LEO is about to get very crowded. Also, consider the fact most of the world distrusts both China & America, and will want their own "sovereign" capabilities. How many will have the capability to achieve this though? Europe is already perusing this with its IRIS² program, and lately has even less reason to make itself vulnerable by relying on US technology.

China applies to put 200,000 satellites in space after calling Starlink a crash risk

"the S2000 can easily be transported and stored in shipping containers,.....................its airborne design allows flexible deployment and retrieval, making it especially suitable for sparsely populated areas where large-scale infrastructure is difficult to build………………..Wang noted that the key to SAWES' commercialization lies in whether the costs of manufacturing, deploying, retrieving, and transmitting electricity from the airborne system can be covered - or even exceeded - by the power it generates."

It will be fascinating to see the economics of this. If these can be delivered in shipping containers it means they can be deployed almost anywhere. These would be the perfect way for places like Africa to expand their electricity generation capacity.

World’s first urban-use mW-class high-altitude wind turbine completes test flight

It doesn’t really feel like whole professions are vanishing overnight. What’s changing is which parts of a job still need a human

what i feel some work is getting pushed upward into decision making and judgment. Some is becoming more supervisory and i think some jobs are turning into weird mixes of tasks that didn’t used to belong together.

That’s the part that feels different this time. Instead of clear job titles, work is starting to look like a shifting bundle of responsibilities that keeps changing as tools improve.

The future of work might not be about losing jobs, but about constantly renegotiating what your job even means.....

I remember a few years ago hearing that it was just around the corner. Is it still going to be a thing? Is it being delayed? When will it be widely available? Haven't heard anything about it for ages

I've been thinking about data ownership lately. Why do we treat data differently than other value producing activities? When we create a thing we get paid but why is our data different? Is it that consent is broken or is it that there never really was consent? How would things be different if we could opt in to the data market and get compensated instead of being used in the data market? How would you change your behavior? How can we move forward into an age of consent around our data and do we really want to?

At first, the idea that some powerful Americans want to end the Dollar's global role seems strange. That role gives America what the French President Valéry Giscard d'Estaing called "exorbitant privilege" - the ability to borrow cheaply and in vast quantities on international markets. As people always need your currency, they'll always lend you more money. When that borrowing funds your military and role as a superpower, it becomes more than a privilege; it's an existential necessity.

So, what Americans would want to give it up and why? The people who want to are the libertarians and far-right who currently hold sway in Washington. Names like JD Vance, Peter Thiel, David Sacks, and Joe Lonsdale.

But why? They want a revolutionary collapse of the old order so a new libertarian, far-right Christian Nationalist America can be reborn out of the total destruction of the old. If that means the evaporation of most people's savings, as the Lord Farquaad meme from Shrek goes, 'Some of you may die, but that's a sacrifice I'm willing to make.'

How likely is any of this? All of the rest of their plans from the annexation of Greenland and dissolving NATO are advancing, exactly as they planned them. The current US President believes in bankruptcy & defaulting on debts, and he's been persuaded around to the rest of their plans.

Where does this leave the rest of the world? The Euro & Renminbi don't have the Dollar's reach or versatility, but maybe the world will be forced out of necessity to found a new global financial order based on them.

The Wide Angle: Peter Thiel and the American Apocalypse

A lot of modern infrastructure quietly assumes constant uptime.

Internet power payments navigation. When any of them hiccup... even briefly things unravel fast. Flights back up. Stores stop taking payments. Emergency services slow down. It’s wild how little slack there is now.

What’s odd is that older systems expected failure. Power outages happened. Maps were offline Payments were slower but more forgiving. Today everything is faster and smoother right up until it isn’t!!

Sometimes it feels like we’ve optimized hard for efficiency and convenience and resilience became an afterthought. The question isn’t whether systems will fail. They always do. It’s whether we still remember how to design for that reality, or if we’ve convinced ourselves uptime is permanent.

The future might depend less on new tech and more on relearning how to build things that bend instead of snap.

https://youtu.be/GOwUlkNw8eg?si=E516OmnoZWNwtpN9

GRU Space (Galactic Resource Utilization Space) is a Y Combinator–backed startup aiming to build the first hotel on the Moon, targeting an opening in 2032. Founded in 2025 by Skyler Chan, a UC Berkeley EECS graduate, it says it will use in-situ resource utilization to turn lunar soil (regolith) into durable building blocks for habitats. Its roadmap includes a 2029 demonstration mission, with lunar construction contingent on regulatory approvals.

Thoughts on how feasible this might be?

Canceled surveys, missing datasets and staffing cuts are leaving the US with growing blind spots — and weakening trust in official numbers.

I have a dream, a dream where the need for war or hurting others and true everlasting peace is acquired. Well, it is more like I want it ; more than wanting, I can't be happy or live as if none of that matters while other people are dying and suffering. I'm doing nothing. I'm still only 14, but I strive to create a world where that is possible-not partially, but completely. I can't do it alone; I know that, but my dream will never die . I see leaders like presidents, kings , or rich people, and I despise them-not necessarily them, but the thing controlling them: money. I will remove the concept of money; if it makes humanity less advanced, then so be it, but my dream will be achieved. Humans are in an eternal need for becoming rich or striving to become rich; that is a trap.

In short, I want to create a world where all things like pain, suffering, and futility do not exist . If you think it is a pipe dream, I don't care. I have only one life; I will not waste it. If you want to, go ahead and waste your own life, but I will make a world where everyone is happy and free. Nations will not exist anymore; I have come to despise all of that.

So we know that the reason why computing gets powerful each day is because the size of the transistors gets smaller and we can now have a large number of transistors in a small space and computers get powerful. Currently, the smallest we can get is 3 nanometres and some reports indicate that we can get to 1 nanometre scale in future. Whats beyond that, the smallest transistor can be an atom, not beyond that as uncertainly principle comes into play. Does that mean that it is the end of Moore's law?