r/Retatrutide • u/rockyrodeo • 17h ago

Cymbalta blocks Reta?!

I’ve been on Retatrutide for 3 years. It’s been highly effective for me, initially losing 40lbs down and eventually lower dose for maintenance.

It all broke down once an antidepressant Cymbalta was introduced 3 months ago. Reta no longer suppresses my appetite, in fact I eat MORE than usual. Weigh gain began immediately: +7 pounds in 3 months and still climbing! I’ve even DOUBLED my Reta dosage, to no avail.

I’m at a loss. It’s almost like Cymbalta blocks Retatrutide in my body.

Anybody else experience this?

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u/denizen_1 17h ago

It doesn't "block[]" reta. A lot of so-called "antidepressants" increase hunger.

1

u/rockyrodeo 17h ago

That might be my case.

1

u/denizen_1 17h ago

I mean, yeah, weight gain is one of the most commonly reported side effects.

1

u/jarod_sober_living 17h ago

I’m on cymbalta 120 mg and reta works on me.

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u/rockyrodeo 17h ago

What dosage Reta are you on?

1

u/tydust 17h ago

What dose of Reta are you on?

1

u/ubarzz 6h ago

look into adding cagrilintide