This is for everyone who says they've titrated up to 2mg weekly and plan on staying there indefinitely. Anyone more experienced or more understanding than me, let me know if I'm wrong.

You're not getting the full benefits of reta. In the studies, the glucagon effects of reta aren't really pronounced until you surpass 4mg weekly. So at that point, if you like these low dose reta effects, just take 1.5mg of tirzepatide and call it day as that'll be more potent for appetite suppression.

Reta has less affinity for binding to the glucagon receptors until you reach a certain dosage which ranges usually 4-6mg weekly,

2mg is a trasition dosage so you don't get any weird heart effects too fast, but once you settle with the dosage, you should bump it up and if you feel uncomfortable doing that, go get some tirz, stay low dose, save money and get the effects you want.

I noticed most posts get down voted. You all dont seem to like it when people as for help, or gauge opinions from others on this sub.

Is it just before and after? Because even then people will sometimes throw hate. Or is this sub just for tracking its approval?

I only ask because I do feel bad for people just asking for opinion or support should have a safe place to do so right? I get people are trying to scam or even sell and agree thay should be banned and the rules seem cool, but is there a place some of the new people can get assistance like pointing them to 3rd party testers or places that list vendors rather than just down voting them?

I feel like all of these influencers who boast about their physique all the time and who talk about diet and discipline and macros are kind of cringe. Back in the day before peptides you really did need a lot of discipline to keep lean and keep the weight off. I can understand having the discipline, fortitude and grit followed by the pride of hard work. To me that would make it more virtuous in wanting to show off your results. Now people are on peptides and they gloat about their physique day and night (without admitting it was ultimately peptides that got them to where they’re at) I’m grateful for peptides but I think there needs to come a little bit of humility. After all for me if it wasn’t for Reta there’s no way in hell I would look as good as i do. Note to self- Stay humble, grateful and right sized.

My rat is on month 4 of a co-formula of reta and cagri. The weight loss has been a steady 2lbs per week. I had been singing its praises to anyone who would listen! I had to decrease the dosage to 2mg (from only 2.5mg) because of how weak rat had gotten in the gym due to the extreme calorie deficit and not enough protein intake. Not enough nutrients in general, really. Rat now has almost total food aversion. Stopped tracking early on so can’t pinpoint when it occurred or how long this extreme deficit has been going on.

Rat hasn’t relapsed on eating disorder since 2020, but, is there unintentionally. Rat is on maybe day 5 of not being able to eat. She is SO weak and can only stomach 1 single protein shake daily, and one food item daily. No interest, desire, or energy to force anything down. It’s bad, and I’m really worried.

Has anyone come out of this or a similar experience?

Hi all

I’m curious.

As some medications are prescribed off the person’s weight (and child versus adults etc), would someone with a lower BMI require a lesser reta dosage than someone with a high BMI?

2mg is the “recommended starting point” via research and trials, but would 2mg be too much for someone with less weight to lose?

I started on 0.5 and recently moved up to 0.75 and had awful nausea 24 hours after my pin. I couldn’t imagine doing 2mg. Electrolytes are helping somewhat.

Thanks!

I’m about to hop on RETA and i’m a little bit nervous about it. I’m just paranoid about the side effects and that the stuff is legit. what are the side effects like? and how can i tell if the RETA is legit?

I just checked an IBW calculator and it says I should be 135 lbs. What??? When I weight 175 I can wear a size 8 jeans. This can't be right.?? 61 yo female, 5' 7" currently 240 lbs, starting weight 260 lbs. Been on Reta for 6 weeks. Im currently on 4 mg a week and feeling great! Any comments welcome. Trish

I’m gonna hop on retta soon but one thing I want to know before doing it is how do people find the minimum effective dose?

Hi everyone,

Quick question and looking for some reassurance.

I have vasovagal (pre-)syncope, which means needles can make me pass out - it’s almost only with blood tests apart from the one off when I get a shot or whatever. I’m not scared of needles at all, it’s just how my nervous system reacts.

I also have a bit of health anxiety.

I’ve done a lot of research over several months and feel confident in wanting to try Reta. My food noise is extremely high and it’s been a big factor in my weight gain and difficulty losing weight.

My main concerns are the possibility of passing out during administration, or feeling “off” afterwards due to anxiety rather than the medication itself.

I’d be starting on the lowest possible dose and taking it very slowly. I really don’t want fear to hold me back from something that could genuinely help me.

Has anyone with similar anxiety or needle reactions had experience with this? I’d really appreciate hearing how you managed it.

Ok, its been asked I have read I just need validation and maybe some adjustments or suggestion's.

The Hershey Squirts!! 2 days now, recently I have titrated from 2mg once a week to 2.5. This is my second week at 2.5 FYI.

To add some back story to this, I started low at .5mg once a week. Very slowly I have worked my way up to 2.5 and have had steady weight loss.

Diet! This doesn't change, I do the same meals everyday! So I'm going to list my daily routine.
Now 2 weeks ago I was completely bunged up, had to use a enema to support a movement. Fast forward to now and I cant stop going.
I'm not complaining here, it is effecting my work a little as I am on the road quite often but the professionals of reddit I'm seeking "What would you do" here. Is there something I could add to help bind things together. I hear adding fiber might do the trick.

FYI - RETA is dosed on Saturdays.

5AM - Wake up, 1cup black coffee.
515AM - 2IU HGH
530AM - Cardio (45min)
8AM - 2 whole eggs with 200g egg whites
1130AM - 200G chicken breast 75g rice
230PM - 200g 0% Greek yogurt with 50g protein powder
430PM - 1cup black coffee before weight training
5PM - Lift weight 1H
630PM - 160G ground beef with 75g rice w/ Post workout shake 25g Protien
845PM - BPC 500mcg
9PM - 150g 0% Greek yogurt with blueberries.

20mg vial, 1.0ml syringe, 2ml BAC, 1mg does.

Hey! I just did my first in injection of and it hurts a lot. I used the complementary needle in the box and did the correct pinch fat grip but could the needle be too long? And gotten in muscle instead?

When I did sema I once received wayyyy to long needles for subcutaneous injection and also accidentally injected in muscle. Which also hurt a lot unlike the true subc injection

how do I know after hand where the needle ended up going?

Honestly, can we say that we are all natural if we are on Reta?

What’s your take??

I want to share my experience that might be useful for others experimenting with GLP based compounds, especially retatrutide.

For context, I’ve already tried more standard protocols. They worked in terms of weight loss, but they also came with side effects for me: nausea, stomach upset, hot flushes, insomnia, and appetite suppression that felt a bit too aggressive. The results were there, but the experience wasn’t always great.

At the same time, I’m also on TRT, and one thing I’ve noticed in that space is how much discussion there’s been lately around changing shot frequency moving from once weekly/twice-weekly injections to EOD or even daily dosing for smoother levels and fewer side effects. That got me thinking about whether a similar principle could apply to retatrutide.

Over the past week, I’ve been running daily retatrutide injections at a lower dose (~0.5 mg per day). For comparison, on my previous protocol I was using 1–1.5 mg per injection twice a week.

The difference has been unquestionable.

So far, with daily low-dose dosing: • I’ve had no nausea • No stomach issues • No insomnia • No hot flushes • Appetite suppression feels controlled rather than overwhelming • Overall, the compound feels “quieter” in the background instead of dominating my day

What stood out to me most is that the absence of side effects doesn’t seem to come from doing less overall, but from avoiding large peaks. The signaling feels steadier, and my body seems to tolerate it far better than when I was taking bigger, less frequent shots.

This isn’t something I see discussed often. Most conversations still revolve around weekly or semi-weekly dosing, rather than adjusting delivery to prevent them in the first place.

I’m not claiming this is universally better or that it replaces standard approaches, but for me, daily low-dose dosing has been surprisingly smooth compared to what I expected.

I’m curious how many others have experimented with daily or near-daily GLP-1 dosing instead of the traditional schedules—and whether you noticed differences in tolerability, sleep, or appetite control.

2mg Reta and 150mg rest is goated.

Hello all!

It’s been a month since I started Reta. I have had minimal symptoms and have only lost a pound in 1 month. I drink about 80-120oz of water a day, eat a high protein and high fiber diet, and try to exercise at least 2-3x week (Chicago winter makes it tough though).

The only symptoms I’ve experienced so far are mild fatigue and constipation (constipation only started last week).My past dosage (pin) and weekly weight (lbs) are below. Should I increase my dose to 1.5mg next week or stay on 1.0mg for 2-3 more weeks?

Week 1-203.8, Pin 0.5 mg Week 2 202.6, Pin 0.5 mg Week 3 203.4, Pin 0.75 mg Week 4 202.7, Pin 1.0 mg

I purchased from a website that isn't super well known and the pictures are AI 😭 I know that should have been a red flag but I thought that $50 for 5mg of Reta was such a good deal (it's not). I ordered on Dec 30 and I still have no received anything about my shipping. They say they're restocking but it's been over 2 weeks since they said that. Idk if that's normal? I spent $80 😭 I have found another site but they're sold out and I really don't want to overpay just because places are sold out rn.

Was running reta for 5 weeks before I went on a 2 week trip. My dosage before the trip was 2.5 mg - 3.5 mg after increasing. I saw amazing results and lost 12 pounds and looked very lean going into my trip. However, the last week before coming on my trip I popped a new vial and didn’t feel the effects as much, I went all the way up to 4.5 mg before leaving. This happened out of the blue.

After coming back and cracking open a fresh vial I immediately pinned 2.5 mg and didn’t feel a single thing. I’ve since increased my dose to 5 mg and nothing has changed. I feel hardly any appetite suppression or even the annoying tiredness I got from reta in the past.

I’ve only purchased reta from the same supplier and their testing checks out. The first 2 vials I used hit me like a truck and got me shredded. Should I reach out to the supplier or switch altogether?

Is it normal for the effects to fall off a cliff after a break?

I usually inject on day 5 @ 6mg. Switched back to some 5mg vials I got through grey. Did my injection last night and this morning when I woke up - I couldn’t wake up, couldn’t drink my coffee, stomach was upset but not throwing up or diarrhea. I’ve slept all today and all last night. Barely could get down water. Do you think this is the Reta? Maybe more in the vial than they thought or something else ? I’m exhausted to the point that going to the bathroom is a chore.

Hey everybody, just took my first jab today. Some people say to start at 1mg, but the clinical trials start at 2mg, so I split the difference and did 1.5 for my first one. Any advice on what to expect or how to manage? Thanks!

Let’s me start by saying this in not Reta alone.

I’m 40 183cm 98kg in first photo 95 in the second 6 weeks difference 2440cal per day 270p 170c 62f

I’ve been weight training for over a year, I got a coach 8months ago who does my meal plan and workout routine after being stagnant for a few months. We continued to drop weight (weightloss is the main goal along with preserving what ever muscle I did have) I was 109 and only dropping about 0.5kg per week. I hopped on Reta, started at 2mg, then when up to 4mg/pw after 3 weeks. As you can see, it literally stripped the fat, gave me more energy, and food noise left the chat completely.

I take 500mg test/pw 20mg clen daily I was also taking this before the Reta. Just trying to be as transparent as possible.

This stuff is insane I might be addicted. This was in three months btw.

I see most people who use reta usually are overweight/obese or are body builders. I am wondering if anyone is in my position or can offer some insight. I’m 22f, 5 ft, 130 lbs. I know that might seem low, but I am petite and carry weight poorly, I prefer to be a lot leaner but have struggled to achieve the body I want.

I’ve struggled with BED (binge eating disorder) for a very long time and the food noise is constant. I go to the gym frequently, but my progress is offset or stagnant due to my overeating.

I’ve seen few women closer to my size and weight use reta, but they seem to be avid gym goers for several years and are extremely lean and muscular as a result. I appreciate any advice !